Case report shows reduced albuminuria in a young woman with ADPKD, implying potential renal benefits.
We report the case of a 23-year-old woman with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and preserved kidney function who was followed with a supervised plant-based ketogenic diet for 11 months. The intervention was associated with a marked reduction in albuminuria (from 80 to 10 mg/g) and a stable estimated glomerular filtration rate (eGFR), with no clinically relevant metabolic or electrolyte disturbances; whereas total kidney volume increased from 617 to 709 cc during follow-up. This case highlights the feasibility, safety, and possible association with favorable renal biomarker changes, warranting further investigation in controlled studies in early-stage ADPKD.
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Alvarado‐Pelayo et al. (2026) studied this question.
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