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July 15, 2026Brazilian Journal of OncologyOpen Access

Pharmacotherapeutic Monitoring of Adverse Drug Reaction in Oncology Outpatient Clinics

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Authors

KSKamilla Vieira Santos da SilvaJCJuliana Leal CavalcantiNSNatalia Farias Santos

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Overview

Observational study evaluates adverse drug reactions in oncology, highlighting the need for pharmacovigilance.

Key Points

  • The study aims to evaluate the frequency of adverse drug reactions (ADRs) linked to antineoplastic drug infusions in outpatient oncology clinics.
  • Observational retrospective study from July 2020 to July 2024
  • Included patients with infusion-related ADRs, totaling 1,073 events
  • Collected data from pharmacovigilance records and electronic medical charts.
  • Highest ADR frequency was associated with paclitaxel (23.02%) and oxaliplatin (20.96%)
  • ADRs were mainly reported in patients aged 61 to 70 years, predominantly female (73%)
  • Pharmaceutical interventions adjusted subsequent treatment in 28% of cases.

Cite This Study

Silva et al. (2026) studied this question.

synapsesocial.com/papers/6a57234488b21df875480107https://doi.org/10.1055/s-0046-1824558
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Occurrence of adverse drug reactions in chemotherapy patients: A cross-sectional study2026
  2. 2Adverse Drug Reactions in Oncology Patients Based on Global Evidence: A Systematic Review2025
  3. 3Pharmacovigilance Practices by Healthcare Providers in Oncology: A Cross-Sectional Study2024
  4. 4Scientific Analysis with a Retrospective Method on the Incidence and Severity of Adverse Drug Reactions in Hospitalized Cancer Patients2024
  5. 5Haematological toxicity associated with antineoplastic drugs: a pharmacovigilance analysis based on the FDA adverse event reporting system database2026