Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 15, 2026International Journal of Molecular SciencesOpen Access

A Review on Environmental Occurrence and Toxicity of Perfluorooctanoic Acid and Its Selected Short-Chain Analogs—Perfluorohexanoic Acid and Perfluorobutanoic Acid

View Full Paper
Ask AI
Bookmark
Share

Authors

IKIzabela KaczmarekKMKatarzyna MokraJMJaromir Michałowicz

Discussion

Loading...

Member takes

Overview

Review examines the toxicity and environmental presence of PFOA and its short-chain analogs, indicating significant health risks.

Key Points

  • This review aims to analyze the environmental occurrence, toxicity, and human exposure risks associated with PFOA and its analogs PFHxA and PFBA.
  • Comprehensive literature review on PFOA, PFHxA, and PFBA
  • Analysis of their environmental presence in air, water, soil, and food
  • Evaluation of their toxicity profiles and health impacts
  • PFOA exhibits significant hepatotoxic and endocrine-disrupting activities
  • PFHxA and PFBA are found to be less toxic than PFOA
  • Environmental accumulation of PFOA and its analogs poses ongoing risks due to their persistence.

Cite This Study

Kaczmarek et al. (2026) studied this question.

synapsesocial.com/papers/6a5723c288b21df87548063ahttps://doi.org/10.3390/ijms27146221
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ubiquitously occurring perfluoroalkyl and polyfluoroalkyl substances: An overview of food and environmental contamination and implications for human health2026
  2. 2Laboratory assays accepted for biological activity disorder, physiological disability, and tissue damage due to the effect of perfluorooctanoic acid contamination.2024
  3. 3Impact of perfluorooctanoic acid (PFOA) and perfluorobutanoic acid (PFBA) on oxidative stress and metabolic biomarkers in human neuronal cells (SH-SY5Y)2024 · 62 citations
  4. 4Linking Analysis to Atmospheric PFAS: An Integrated Framework for Exposure Assessment, Health Risks, and Future Management Strategies2025
  5. 5Structural drivers of per- and polyfluoroalkyl substances environmental fate, bioaccumulation kinetics, and sub-cellular toxicity: A systematic review of legacy and emerging alternatives2026