What question did this study set out to answer?

This research aims to compare the time to achieve a graftable wound bed between intact fish skin grafts and a synthetic matrix in traumatic wounds.

July 15, 2026European Burn JournalOpen Access

Retrospective Cohort Study Evaluating Time to Graft Between Intact Fish Skin Grafts and a Synthetic Matrix Used in Complex Full-Thickness Acute Traumatic and Burn Wounds

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Retrospective cohort study finds intact fish skin grafts lead to faster graftable wound beds than synthetic matrix.

This research aims to compare the time to achieve a graftable wound bed between intact fish skin grafts and a synthetic matrix in traumatic wounds.
Matched sample of patients receiving intact fish skin grafts versus synthetic matrix.
Conducted retrospective analysis with chart reviews for primary outcomes.
Utilized regression analysis to adjust for potential confounders.
Patients with intact fish skin grafts had a mean time to graftable wound bed of 13.9 days versus 29.1 days for synthetic matrix (p < 0.001).
All intact fish skin graft patients received negative pressure wound therapy at implantation compared to only 50% in the synthetic matrix group (p = 0.001).
The synthetic matrix group had significantly larger total body surface area and wound size compared to the intact fish skin graft group (p < 0.001).

Hill et al. (2026) studied this question.

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