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July 15, 2026G3 Genes Genomes GeneticsOpen Access

A marine-derived fungal genome of Annulohypoxylon annulatoides reveals AT-rich isochores with putative regulatory functions

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Authors

CKChe-Yu Thiat-Ut KuoLYLiu YCYCheng-Ju Yang

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Overview

Randomized trial identifies distinct genomic features in coastal fungus, suggesting adaptive functions for environmental tolerance.

Key Points

  • This research aims to explore the genomic characteristics of the coastal fungus Annulohypoxylon annulatoides and their potential role in stress tolerance.
  • Selected coastal isolate RYS0019 for phenotypic and genomic study from 56 collected fungi.
  • Conducted experiments under varying salinity, temperature, and UV stress treatments to assess growth dynamics.
  • Generated a de novo genome assembly of 41.8 Mbp and compared it with 15 other genomes from the Hypoxylaceae family.
  • Identified AT-rich isochores that are repeat-enriched and gene-poor in the Annulohypoxylon genomes.
  • Core gene content and Pfam domain profiles were conserved despite AT content variation.
  • Notable structural features were found indicating potential regulatory roles, with implications for genome organization.

Cite This Study

Kuo et al. (2026) studied this question.

synapsesocial.com/papers/6a57245a88b21df875480ce1https://doi.org/10.1093/g3journal/jkag192
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