Theoretical framework explores HIV latency's biophysical basis in cellular dynamics, suggesting treatments.
The human body is saturated with electricity and magnetism. From the millivolt membrane potentials that gate every ion channel to the 40\,Hz gamma oscillations of cortical and immune networks, electromagnetism is not an external influence on biology but its native language. This paper develops the biophysical foundations of a framework proposed in a companion theoretical paper: that HIV latency isan attractor state sustained by the chronic gradient load of simultaneously maintaining cellular identity and silencing anintegrated provirus. This dual burden narrows the cell's tolerance margin relative to healthy counterparts. The Gradient Indeterminacy (I-G) principle formalises this margin; the Drain Vortex mechanism describes its collapse dynamics. A consequence follows: a perturbation sufficient to destabilise the latent attractor may leave healthy cells unaffected. We propose a Multi-Variant Pulse Protocol (PPMV, by its Spanish acronym) as an implementation framework, and present convergent empirical signals --- encountered after the framework was constructed --- that support the differential vulnerability hypothesis. The biophysical parameter ranges for the PPMV protocol are grounded in existing clinical and experimental data.
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Daniel Avilés Hurtado (2026) studied this question.
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