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Drug-resistant bacteria have been on the offensive for years, with few new compounds available for a counterattack. But at a recent meeting, pharmaceutical companies introduced a promising crop of new antibiotics, with a variety of ways to beat back resistance. Whether companies have enough incentives to develop the most effective anti-resistance strategies—narrow-spectrum antibiotics—remains an open question. See sidebar (p. 725).
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Robert F. Service (1995) studied this question.