Key result
History of amputation (P=0.003) and angina (P<0.001) increased the risk of unfavorable outcomes in PAD patients, while statin and aspirin use (P<0.001) were associated with better outcomes.
Why the study?
The study aimed to evaluate predictors of unfavorable outcomes in outpatients with lower extremity peripheral artery disease during 3-year follow-up.
Cohort (n=585)
In patients with peripheral artery disease, history of amputation and angina predict worse outcomes, whereas cardiologist follow-up and guideline-directed medical therapy (statins, aspirin) are associated with reduced complications.
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Сумин et al. (2020) conducted a cohort in Peripheral atherosclerosis / Peripheral arterial disease (n=585). Clinical predictors (angina, history of amputation, statin/aspirin use) vs. Absence of these predictors was evaluated on Unfavorable outcome (death, non-fatal myocardial infarction and stroke, limb amputation). History of amputation (P=0.003) and angina (P<0.001) increased the risk of unfavorable outcomes in PAD patients, while statin and aspirin use (P<0.001) were associated with better outcomes.
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