Key result
Progression of carotid atherosclerosis after CABG was significantly associated with smoking (p=0.04), poorly controlled diabetes (p=0.04), elevated inflammatory biomarkers (p<0.05), and hypoechoic plaques.
Why the study?
Does the use of cardiopulmonary bypass and other clinical risk factors predict the progression of carotid atherosclerosis in patients undergoing coronary artery bypass grafting?
Observational (n=74)
Does the use of cardiopulmonary bypass and other clinical risk factors predict the progression of carotid atherosclerosis in patients undergoing coronary artery bypass grafting?
In patients undergoing CABG, poorly controlled diabetes, elevated inflammatory biomarkers, hypoechoic carotid plaques, and the use of cardiopulmonary bypass are associated with the progression of carotid atherosclerosis.
Carotid atherosclerosis may progress after CABG in stable CAD; leaves open whether cardiopulmonary bypass influences rates.
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Sokolova et al. (2019) conducted an observational in Stable coronary heart disease after coronary artery bypass grafting (n=74). Risk factors (smoking, diabetes, elevated inflammatory biomarkers, hypoechoic plaques, cardiopulmonary bypass) vs. Absence of these risk factors was evaluated on Progression of carotid atherosclerosis (de novo plaques, IMT thickening ≥0.5 mm, or increased stenosis of existing plaque). Progression of carotid atherosclerosis after CABG was significantly associated with smoking (p=0.04), poorly controlled diabetes (p=0.04), elevated inflammatory biomarkers (p<0.05), and hypoechoic plaques.
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