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To assess the efficacy of ultrasound-guided platelet-rich plasma injection compared to placebo for refractory iliotibial band syndrome.

July 16, 2026Apunts Sports MedicineOpen Access

Ultrasound-guided platelet-rich plasma injection for refractory iliotibial band syndrome: First prospective, randomized, placebo-controlled trial

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To assess the efficacy of ultrasound-guided platelet-rich plasma injection compared to placebo for refractory iliotibial band syndrome.
Prospective, randomized, double-blind, placebo-controlled trial.
Sixty patients aged 18-50 with refractory ITBS received either PRP (n=30) or placebo (n=30) injections.
Primary outcome was change in VAS pain score at 6 months.
PRP group had a mean reduction of 2.2 points in VAS pain scores at 6 months (p<0.001).
Significant improvements noted in functional outcomes and return-to-sport rates in the PRP group.
Higher patient satisfaction rates were observed in the PRP group.

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Randomized trial evaluates ultrasound-guided PRP injection efficacy in refractory iliotibial band syndrome, suggesting it may improve outcomes.

Elazab et al. (2026) studied this question.

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Randomized trial evaluates ultrasound-guided PRP injection efficacy in refractory iliotibial band syndrome, suggesting it may improve outcomes.