Key result
Positive blood culture rates in pediatric congenital IE rise to 100% over two decades.
Population
35 children with congenital heart disease and infective endocarditis between January 1965 and December 1984.
Design
Case_series
Authors
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The spectrum of infective endocarditis in children with congenital heart disease changed over two decades, with improved diagnostic speed and culture positivity, while mortality remained concentrated in infants with heart failure.
Observational (n=35)
Absolute Event Rate: 100% vs 60%
p-value: p=<0.05
The spectrum of infective endocarditis in children with congenital heart disease changed over two decades, with improved diagnostic speed and culture positivity, while mortality remained concentrated in infants with heart failure.
Geva et al. (1988) conducted an observational in Infective endocarditis in children with congenital heart disease (n=35). Latter decade (1975-1984) vs. Former decade (1965-1974) was evaluated on Positive blood cultures (p=<0.05). Diagnosis of infective endocarditis in children with congenital heart disease improved over 20 years, with positive blood cultures increasing from 60% to 100% in the second decade (P<0.05).