Key result
Early application of extracorporeal membrane oxygenation successfully provided hemodynamic support and facilitated survival in a patient with severe malignant hyperthermia and cardiac arrest.
Why the study?
Does extracorporeal membrane oxygenation provide effective hemodynamic support in a patient with severe malignant hyperthermia and cardiac arrest?
Case Report (n=1)
No
Does extracorporeal membrane oxygenation provide effective hemodynamic support in a patient with severe malignant hyperthermia and cardiac arrest?
ECMO can be successfully used to provide hemodynamic support during cardiac arrest caused by severe malignant hyperthermia when conventional CPR fails.
May support early ECMO in refractory malignant hyperthermia arrest; hypothesis-generating and requires prospective validation.
Malignant hyperthermia (MH) may lead to metabolic crisis of skeletal muscle in susceptible individuals following exposure to triggering agents such as volatile anesthetics or depolarizing muscle relaxants. MH is a rare and a potentially lethal disease, which can lead to cardiac arrest. We report a case of severe MH, in which the rapidly evolving signs of hypermetabolism eventually resulted in cardiac arrest. Despite conventional treatments following cardiopulmonary resuscitation, the patient's vital signs did not improve. Therefore, we applied extracorporeal membrane oxygenation for providing hemodynamic support.
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Huh et al. (2017) conducted a case report in Severe malignant hyperthermia and cardiac arrest (n=1). Extracorporeal membrane oxygenation (ECMO) was evaluated on Survival and hemodynamic recovery. Early application of extracorporeal membrane oxygenation successfully provided hemodynamic support and facilitated survival in a patient with severe malignant hyperthermia and cardiac arrest.
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