Key result
Opioid consumption within 30 postoperative days is linked to new persistent opioid use.
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Early postoperative opioid consumption was associated with NPOU; leaves open whether early interventions reduce persistence.
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Gözde Çelik (2026) studied this question. Opioid consumption within the first 30 postoperative days is associated with new persistent opioid use, though its causal interpretation as a mediator, marker, or consequence is debated.
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