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May 7, 2010Coronary Artery Disease

In STEMI patients treated with primary PCI and abciximab, transradial access was associated with fewer puncture site hematomas than transfemoral access (1.2% vs 9.4%, P<0.001).

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Why the study?

Does the transradial approach reduce bleeding complications compared to the transfemoral approach in STEMI patients undergoing primary PCI with abciximab?

Population

1,086 STEMI patients transferred for primary PCI and treated with abciximab, from the EUROTRANSFER registry…

Comparison

Transradial approach for primary PCI vs Transfemoral approach for primary PCI

Design

Cohort

Key result

In STEMI patients treated with primary PCI and abciximab, transradial access was associated with fewer puncture site hematomas than transfemoral access (1.2% vs 9.4%, P<0.001).

Authors

ZSZbigniew SiudakBZBarbara ZawiślakADArtur Dziewierz

Discussion

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Member takes

Overview

May support radial access in STEMI PCI; leaves open practice change without randomized confirmation.

Study Design

Type

Observational (n=1,086)

Multicenter

Yes

Structured PICO

Does the transradial approach reduce bleeding complications compared to the transfemoral approach in STEMI patients undergoing primary PCI with abciximab?

P
Population
1,086 STEMI patients treated with primary PCI and abciximab from a European registry, comparing transradial versus transfemoral access.
E
Exposure
Transradial approach for primary PCI
C
Comparator
Transfemoral approach for primary PCI
O
Outcome
Bleeding complications (puncture site hematomas and major bleeding requiring transfusion)safety

Main Result

Odds Ratio: 3.54

Absolute Event Rate: 1.2% vs 9.4%

p-value: p=<0.001

In STEMI patients undergoing primary PCI with abciximab, the transradial approach significantly reduces local bleeding complications compared to the transfemoral approach.

Cite This Study

Siudak et al. (2010) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=1,086). Transradial approach vs. Transfemoral approach was evaluated on Puncture site hematomas (OR 3.54, p=<0.001). In STEMI patients treated with primary PCI and abciximab, transradial access was associated with fewer puncture site hematomas than transfemoral access (1.2% vs 9.4%, P<0.001).

synapsesocial.com/papers/6a5ac2858c5001fd9054f1f5https://doi.org/10.1097/mca.0b013e32833aa6d1
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