Key result
Bicuspid aortic valve repair matches tricuspid repair for 4-year freedom from reintervention.
Why the study?
Surgical repair for regurgitant bicuspid aortic valve is promising but underutilized due to perceived complexities and lack of long-term data.
Does aortic valve repair with external annuloplasty provide comparable clinical and echocardiographic outcomes in patients with bicuspid aortic valves compared to those with tricuspid aortic valves?
Cohort (n=132)
No
Does aortic valve repair with external annuloplasty provide comparable clinical and echocardiographic outcomes in patients with bicuspid aortic valves compared to those with tricuspid aortic valves?
Surgical repair of bicuspid aortic valves using extra-aortic annuloplasty yields excellent mid-term survival and freedom from severe regurgitation that is comparable to results seen in tricuspid aortic valve repair.
Surgical repair for regurgitant bicuspid aortic valve (BAV) is promising but underutilized due to perceived complexities and lack of long-term data. This study evaluated the efficacy of valve-sparing root remodeling (VSRR) or isolated valve repair combined with calibrated external ring annuloplasty in BAV versus tricuspid aortic valve (TAV) patients. All patients operated on for aortic regurgitation and/or aneurysm at our institution between 2014 and 2022 were included and entered into the Aortic Valve Insufficiency and ascending aorta Aneurysm InternATiOnal Registry (AVIATOR). Patients with successful repair at index surgery (100% in the BAV group, 93% in the TAV group, p = 0.044) were included in a systemic follow-up with echocardiography at regular intervals. Among 132 patients, 58 were in the BAV (44%) and 74 in the TAV group (56%). There were no inter-group differences in preoperative patient characteristics, except BAV patients being significantly younger (47 ± 18 y vs. 60 ± 14 y, p < 0.001) and having narrower aortic roots at the level of sinuses (41 ± 6 mm vs. 46 ± 13 mm, p < 0.001) and sinotubular junctions (39 ± 10 mm vs. 42 ± 11, p = 0.032). No perioperative deaths were recorded. At four years, there was no significant difference in terms of overall survival (96.3% BAV vs. 97.2% TAV, p = 0.373), freedom from valve reintervention (85.2% BAV vs. 93.4% TAV, p = 0.905), and freedom from severe aortic regurgitation (94.1% BAV vs. 82.9% TAV, p = 0.222). Surgical repair of BAV combined with extra-aortic annuloplasty can be performed with low perioperative morbidity and mortality and excellent mid-term results which are comparable to TAV repair.
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Barić et al. (2024) conducted a cohort in Aortic regurgitation and/or ascending aorta aneurysm (n=132). Bicuspid aortic valve (BAV) repair with extra-aortic annuloplasty vs. Tricuspid aortic valve (TAV) repair with extra-aortic annuloplasty was evaluated on Freedom from aortic valve reintervention at 4 years (p=0.905). Surgical repair of bicuspid aortic valves with extra-aortic annuloplasty yielded comparable freedom from valve reintervention at 4 years vs tricuspid valve repair (85.2% vs 93.4%, p=0.905).
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