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Investigates cerebellar atrophy frequency and outcomes in pediatric opsoclonus-myoclonus-ataxia syndrome, highlighting significant implications.
Pediatric-onset opsoclonus-myoclonus-ataxia syndrome (POOMAS) is a rare, neuroinflammatory syndrome that targets the cerebellum and can cause irreversible cerebellar structural changes, namely cerebellar atrophy. We investigated the frequency of cerebellar atrophy, as well as associated risk factors and functional outcome measures, using the largest active POOMAS registry.
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MacRae et al. (2026) studied this question.
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