Estimating Intervention Effects With Difference-in-Differences

Alyssa Bilinski; Shuo Feng; Laura A. Hatfield

doi:10.1001/jama.2026.12551

July 16, 2026JAMA

Estimating Intervention Effects With Difference-in-Differences

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Key Points

This guide aims to explain the difference-in-differences method and its utility in estimating intervention effects while minimizing biases.
Overview of the difference-in-differences methodology
Comparison of outcomes before and after intervention
Contrast between intervention and control settings.
Provides a systematic approach to measure intervention impacts
Highlights potential biases in intervention assessments and how to mitigate them.

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Implication

Guide to statistics explores difference-in-differences method for estimating intervention effects, highlighting its applications.

Abstract

This Guide to Statistics and Methods provides an overview of the difference-in-differences method, a tool for addressing potential biases by contrasting the change in the outcome of interest from before an intervention to after, between settings experiencing and those not experiencing the intervention.

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Cite This Study

Bilinski et al. (2026) studied this question.

synapsesocial.com/papers/6a5b191118557b26c203ab98 https://doi.org/10.1001/jama.2026.12551

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Estimating Intervention Effects With Difference-in-Differences

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Implication

Abstract

Discussion

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Estimating Intervention Effects With Difference-in-Differences

Key Points

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Implication

Abstract

Discussion

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