Key result
GDMT and shared decision-making enable conditional return to play in athlete's heart overlapping with cardiomyopathy.
Why the study?
Distinguishing physiologic athletic remodeling from early cardiomyopathy is particularly challenging when structural abnormalities coexist with elite functional performance and electrical instability.
Case Report (n=1)
Elite athletic performance does not exclude early cardiomyopathy, and return-to-play decisions in gray-zone phenotypes require shared decision-making, multidisciplinary input, and robust emergency action planning.
Answers are grounded in this paper and cite their sources.
Shared decision-making essential for gray-zone LV dilation in athletes; leaves open optimal risk stratification pending larger cohorts.
BACKGROUND: Distinguishing physiologic athletic remodeling from early cardiomyopathy is particularly challenging when structural abnormalities coexist with elite functional performance and electrical instability. CASE SUMMARY: : 52.5 mL/kg/min) without inducible arrhythmias. DISCUSSION: This case highlights the physiologic-pathologic overlap between athlete's heart and early nonischemic cardiomyopathy complicated by electrical instability. TAKE-HOME MESSAGES: Elite performance does not exclude cardiomyopathy. Return-to-play decisions in gray-zone phenotypes require shared decision-making, multidisciplinary input, and robust emergency action planning.
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Mutebi et al. (2026) conducted a case report in Severe left ventricular dilation / early nonischemic cardiomyopathy (n=1). Guideline-directed medical therapy and shared decision-making was evaluated. In an 18-year-old elite athlete, severe LV dilation with electrical instability and preserved contractile reserve highlighted the overlap between physiologic remodeling and early cardiomyopathy.
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