Female sex was associated with a higher prevalence of insomnia following PCI compared to male sex (47% vs 28%, P<0.001), which persisted over 12 months and correlated with poorer mental health.
Cohort (n=3,417)
Yes
What is the prevalence and trajectory of insomnia after PCI, and how does it associate with self-reported health status?
Insomnia is highly prevalent and persistent following PCI, particularly in women, and is associated with poorer mental and physical health outcomes.
Absolute Event Rate: 47% vs 28%
p-value: p=<0.001
Abstract Aims Insomnia is an independent risk factor for coronary artery disease (CAD). Persistent sleep difficulties after percutaneous coronary intervention (PCI) may hinder recovery, however, studies investigating factors contributing to insomnia in a longitudinal perspective are scarce. Therefore, we aimed to describe and determine: i) the prevalence of insomnia in women and men with CAD after PCI; ii) changes in insomnia scores over time and iii) the association between insomnia, self-reported health status and individual factors 6- and 12 months post-PCI. Methods and results Large-scale, prospective, multicentre cohort study on patients after PCI (N=3,417). Patient-reported outcomes were collected during index hospitalization and 2-, 6-, and 12-months post-PCI (T0-T3 respectively). Insomnia was assessed with the Minimal Insomnia Symptom Scale, and self-reported health status with RAND-12 and the Seattle Angina Questionnaire. Clinical characteristics were collected from The Norwegian Registry of Invasive Cardiology and patients’ medical records. The prevalence of insomnia was high (women 47% vs. men 28%) at T0 (p0.001) and remained at similar levels (T1-T3). Reduced mental health in men (p0.001, T2 and T3) and women (p=0.013 (T2) and p=0.038 (T3)) and physical health in women (p=0.013 (T2) and p=0.011 (T3)) were associated with insomnia. Moreover, insomnia at previous timepoints was associated with insomnia at later timepoints for both sexes (p0.001 for all comparisons). Conclusion Insomnia is highly prevalent following PCI, particularly among women, persisting over time, and related to poorer mental health in men and women. Greater attention should be directed toward early screening and targeted sleep interventions in both sexes.
Pettersen et al. (Wed,) conducted a cohort in Coronary artery disease after PCI (n=3,417). Female sex vs. Male sex was evaluated on Prevalence of insomnia at index hospitalization (p=<0.001). Female sex was associated with a higher prevalence of insomnia following PCI compared to male sex (47% vs 28%, P<0.001), which persisted over 12 months and correlated with poorer mental health.