Key result
IBS is linked to significantly higher anxiety, depression, and suicidal ideation compared to controls.
Why the study?
Irritable bowel syndrome is linked to psychological conditions, but few studies had explored these associations in the Iranian population using standardized tools.
Does irritable bowel syndrome increase the severity of anxiety, depression, and suicidal ideation compared to controls?
Case-Control (n=90)
No
Does irritable bowel syndrome increase the severity of anxiety, depression, and suicidal ideation compared to controls?
Absolute Event Rate: 27.53% vs 14.93%
p-value: p=< 0.001
Irritable bowel syndrome is strongly associated with increased psychiatric comorbidities, including anxiety, depression, and suicidal ideation.
Background: Irritable bowel syndrome (IBS) is linked to psychological conditions such as anxiety, depression, and suicidal ideation. However, few studies have explored these associations in the Iranian population using standardized tools. Objective: The objective of this study was to evaluate the prevalence and severity of anxiety, depression, and suicidal ideation in IBS patients compared to controls. Materials and Methods: A case–control study was conducted at Aliben Abi Taleb Hospital in 2020. Ninety participants (45 IBS cases, 45 controls) completed the Beck Depression Inventory, Beck Anxiety Inventory, and Beck Suicide Inventory. Results: IBS patients exhibited significantly higher mean scores for anxiety (27.53 vs. 14.93, P < 0.001), depression (14.96 vs. 8.16, P < 0.001), and suicidal ideation (5.31 vs. 3.42, P = 0.011) compared to controls. Conclusion: IBS is strongly associated with increased psychiatric comorbidities, highlighting the need for integrated psychological care in IBS management.
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Zivarifa et al. (2025) conducted a case-control in Irritable bowel syndrome (n=90). Irritable bowel syndrome vs. controls was evaluated on anxiety score (p=< 0.001). Irritable bowel syndrome was associated with significantly higher mean scores for anxiety (27.53 vs. 14.93, P<0.001), depression (14.96 vs. 8.16, P<0.001), and suicidal ideation compared to controls.
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