Key result
Methylprednisolone, antimicrobials, and cardioprotective therapy yield substantial improvement in a viral myocarditis case.
Case Report (n=1)
This case highlights the diagnostic complexity of viral myocarditis presenting as myocardial infarction with non-obstructive coronary arteries (MINOCA) and the efficacy of a multidisciplinary treatment approach.
May support multidisciplinary therapy in viral myocarditis mimicking MINOCA; hypothesis-generating and requires prospective validation.
A 59-year-old male presented to the emergency department with acute-onset chest pain described as precordial tightness radiating to the left upper extremity, persisting for approximately 24 hours. His symptoms were accompanied by several days of fever and generalized body aches. Laboratory evaluation revealed a marked inflammatory response and significantly elevated cardiac injury biomarkers. Electrocardiography (ECG) demonstrated ST-segment elevation with pathological Q waves in V1-V3, while angiography excluded obstructive coronary disease. The patient was treated with methylprednisolone, antiviral therapy (ganciclovir), empirical antibiotic therapy (ampicillin), and cardioprotective treatment including cyclic adenosine monophosphate meglumine for eight days. This regimen resulted in substantial improvement in clinical symptoms and laboratory parameters. This case highlights the diagnostic complexity of viral myocarditis presenting as myocardial infarction with non-obstructive coronary arteries, particularly in geographic regions endemic for tick-borne infections. A multidisciplinary approach involving cardiology, infectious disease expertise, and laboratory diagnostics is essential for timely intervention and optimal outcomes in patients with myocarditis presenting as myocardial infarction.
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Piao et al. (2026) conducted a case report in Suspected tick-borne viral infection-associated myocarditis (n=1). Methylprednisolone, ganciclovir, ampicillin, and cyclic adenosine monophosphate meglumine was evaluated on Improvement in clinical symptoms and laboratory parameters. Treatment with methylprednisolone, ganciclovir, ampicillin, and cardioprotective therapy for 8 days resulted in substantial clinical and laboratory improvement in a patient with viral myocarditis.
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