Combined physical training improved cardiac autonomic response post-bronchoprovocation test in asthmatic adolescents without EIB from the first minute, and after 10 minutes in those with EIB (p<0.001).
Does combined physical training improve cardiac autonomic modulation following bronchoprovocation in asthmatic adolescents with and without EIB?
Combined physical training improves cardiac autonomic recovery following exercise-induced bronchoprovocation in asthmatic adolescents, with faster recovery observed in those without exercise-induced bronchoconstriction.
p-value: p=<0.001
OBJECTIVE: Exercise-induced bronchoconstriction (EIB) is defined as the acute narrowing of the lower respiratory airways after exercise. This study aimed to verify the behavior of cardiac autonomic modulation after combined training in asthmatic adolescents with and without EIB. METHODS: ) from baseline, measured at 5, 10, 15, and 30 min after a treadmill bronchoprovocation test. Heart rate variability (HRV) was recorded at rest and 40 min after the bronchoprovocation test. Both assessments were performed before and after the concurrent training program. Generalized equation estimation (GEE) was performed to evaluate the interaction between the groups at the evaluated times. RESULTS: There was sympathetic impairment (mean RR interval and heart rate) in patients with and without EIB after the bronchoprovocation test in the 40 min evaluated, which improved after combined training at all times evaluated in patients without EIB and after 10 min in those with EIB (p < 0.001). The parasympathetic component (percentage of adjacent intervals over 50 msPNN50) was not altered after the bronchoprovocation test in individuals without EIB before and after training. In individuals with EIB, pNN50 was changed 40 min after the bronchoprovocation test before training and showed improvement after 10 min (p < 0.001) in the reassessment. CONCLUSION: An improvement in autonomic response was observed in asthmatic adolescents without EIB following combined physical training, evident from the first minute post-bronchoprovocation test, whereas in those with EIB, this improvement became apparent after 10 min.
Couto et al. (Wed,) conducted a other in Asthma with and without exercise-induced bronchoconstriction. Combined training program vs. Baseline (before training) was evaluated on Cardiac autonomic modulation (HRV, mean RR interval, heart rate, pNN50) (p=<0.001). Combined physical training improved cardiac autonomic response post-bronchoprovocation test in asthmatic adolescents without EIB from the first minute, and after 10 minutes in those with EIB (p<0.001).