Why the study?
Chronic kidney disease awareness remains low, and urine albumin testing may be underused even among adults with established cardiometabolic risk.
Population
6,671 US adults with diabetes, hypertension, or both, without self-reported kidney disease
Comparison
Hypertension alone vs diabetes alone vs both conditions
Design
Nationally representative cross-sectional study (NHANES)
Key result
Concurrent diabetes and hypertension was associated with a higher prevalence of albuminuria compared to hypertension alone (PR 2.38; 95% CI 2.07-2.74) among US adults without known kidney disease.
Authors
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Higher albuminuria prevalence with diabetes plus hypertension may support screening consideration; extends cross-sectional NHANES data but leaves outcome benefits open.
Cross-Sectional (n=6,671)
Yes
Relative Risk: 2.38 (95% CI 2.07–2.74)
Absolute Event Rate: 32.6% vs 11.7%
A substantial proportion of US adults with hypertension and/or diabetes have undetected albuminuria, emphasizing the need for routine urine albumin testing to improve kidney-risk assessment in these high-risk groups.
Li et al. (2026) conducted a cross-sectional in Hypertension, diabetes, or both (n=6,671). Concurrent diabetes and hypertension vs. Hypertension alone was evaluated on Study-detected albuminuria (urinary albumin-to-creatinine ratio ≥30 mg/g) (PR 2.38, 95% CI 2.07-2.74). Concurrent diabetes and hypertension was associated with a higher prevalence of albuminuria compared to hypertension alone (PR 2.38; 95% CI 2.07-2.74) among US adults without known kidney disease.