Key result
Visceral fat accumulation and abdominal obesity contribute significantly to global cardiometabolic risk through mechanisms including adipocytokine dysregulation, insulin resistance, lipotoxicity, and ectopic fat deposition in the heart.
Design
Review
Authors
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Current metabolic syndrome criteria may underestimate visceral fat–driven risk; leaves open whether ectopic fat imaging refines stratification or outcomes.
This review emphasizes the need to evaluate global cardiometabolic risk individually, focusing on the impact of abdominal obesity and ectopic cardiac fat.
Michio Shimabukuro (2008) conducted a review in Cardiometabolic risk and abdominal obesity. Abdominal obesity and visceral fat was evaluated. Visceral fat accumulation and abdominal obesity contribute significantly to global cardiometabolic risk through mechanisms including adipocytokine dysregulation, insulin resistance, lipotoxicity, and ectopic fat deposition in the heart.
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