Key result
Reduced LVEF (OR 3.6) predicted early mortality, while CAD (HR 6.44), COPD (HR 4.21), and renal insufficiency (HR 1.8) predicted late mortality after pericardiectomy for constrictive pericarditis.
Population
97 consecutive patients with chronic constrictive pericarditis undergoing surgical treatment, mean age 60.0…
Design
Cohort
Follow-up
median 1.23 ± 3.96 years (mean 3.08 ± 3.96 years)
Authors
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High mortality after pericardiectomy for constrictive pericarditis with ventricular dysfunction and CAD as predictors warrants careful selection; retrospective data leaves open prospective validation.
Cohort (n=97)
No
Odds Ratio: 3.6
p-value: p=0.01
Pericardiectomy for constrictive pericarditis carries significant mortality risk, with early death driven by ventricular dysfunction (reduced LVEF, RV dilation) and late death driven by comorbidities (CAD, COPD, renal insufficiency).
Busch et al. (2015) conducted a cohort in Chronic constrictive pericarditis (n=97). Preoperative risk factors (reduced LVEF, RV dilatation, CAD, COPD, renal insufficiency) vs. Absence of risk factors was evaluated on Early mortality (associated with reduced LVEF) (OR 3.6, p=0.01). Reduced LVEF (OR 3.6) predicted early mortality, while CAD (HR 6.44), COPD (HR 4.21), and renal insufficiency (HR 1.8) predicted late mortality after pericardiectomy for constrictive pericarditis.
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