Key result
Type D personality was associated with a higher odds of endothelial dysfunction at baseline (65% vs 44%; OR 3.03, 95% CI 1.04-8.80) and at 12 months (OR 3.43) in patients with coronary artery disease.
Why the study?
Does Type D personality predict impaired endothelial function in patients with coronary artery disease?
Population
180 patients with coronary artery disease (37 with Type D personality, 143 non-Type D)
Comparison
Type D personality vs Non-Type D personality
Design
Cohort
Follow-up
12 months
Authors
Loading...
Type D screening may flag persistent endothelial risk in CAD; hypothesis-generating for interventions, does not yet change practice.
Cohort (n=180)
Does Type D personality predict impaired endothelial function in patients with coronary artery disease?
Odds Ratio: 3.03 (95% CI 1.04–8.8)
Absolute Event Rate: 65% vs 44%
Type D personality is an independent predictor of persistent endothelial dysfunction in patients with coronary artery disease, highlighting a potential mechanism linking psychological factors to adverse cardiovascular outcomes.
Denollet et al. (2018) conducted a cohort in Coronary artery disease (n=180). Type D personality vs. Non-Type D personality was evaluated on Endothelial dysfunction (FMD <5.5%) at baseline (OR 3.03, 95% CI 1.04-8.80). Type D personality was associated with a higher odds of endothelial dysfunction at baseline (65% vs 44%; OR 3.03, 95% CI 1.04-8.80) and at 12 months (OR 3.43) in patients with coronary artery disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: