Key result
Roux-en-Y gastric bypass resulted in a 29% incidence of reactive hypoglycemia at 1 year compared to 14% with sleeve gastrectomy (P=0.079).
Why the study?
Does Roux-en-Y gastric bypass compared to sleeve gastrectomy affect the incidence of reactive hypoglycemia in patients undergoing bariatric surgery?
Population
120 eligible patients at an outpatient obesity clinic in a university hospital in Rome, Italy
Comparison
Roux-en-Y gastric bypass (RYGB) vs Sleeve gastrectomy (SG)
Design
RCT, 1:1, open-label
Follow-up
12 months
Authors
Loading...
No significant difference in reactive hypoglycemia incidence; leaves open whether bypass increases severe events requiring hospitalization.
RCT (n=120)
Open-label
1:1
No
Does Roux-en-Y gastric bypass compared to sleeve gastrectomy affect the incidence of reactive hypoglycemia in patients undergoing bariatric surgery?
Absolute Event Rate: 29% vs 14%
p-value: p=0.079
While reactive hypoglycemia is common after both procedures, Roux-en-Y gastric bypass is associated with more severe hypoglycemic episodes requiring hospitalization compared to sleeve gastrectomy.
Capristo et al. (2018) conducted an RCT in Obesity (n=120). Roux-en-Y gastric bypass (RYGB) vs. Sleeve gastrectomy (SG) was evaluated on incidence of reactive hypoglycemia (<3.1 mmol/L after 75-g oral glucose load) at 1 year after surgery (p=0.079). Roux-en-Y gastric bypass resulted in a 29% incidence of reactive hypoglycemia at 1 year compared to 14% with sleeve gastrectomy (P=0.079).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: