Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells

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SARS-CoV-2 infection of human small intestinal epithelial cells induces mucosal infiltration by activated CD8+ T cells, potentially driving the gastrointestinal symptoms associated with COVID-19. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Malte Lehmann; Kristina Allers; Claudia Heldt; Jenny Meinhardt; Franziska Schmidt; Yasmina Rodriguez‐Sillke; Désirée Kunkel; Michael Schümann; Chotima Böttcher; Christiane Stahl‐Hennig; Sefer Elezkurtaj; Christian Bojarski; Helena Radbruch; Victor M. Corman; Thomas Schneider; Christoph Loddenkemper; Verena Moos; Carl Weidinger; Anja A. Kühl; Britta Siegmund

doi:10.1038/s41385-021-00437-z

Abstract

T cells are activated upon infection of intestinal epithelial cells with SARS-CoV-2, providing one possible explanation for gastrointestinal symptoms associated with COVID-19.

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Lehmann et al. (2021) studied this question.

synapsesocial.com/papers/6a5be37923a8459aadb97d3f https://doi.org/10.1038/s41385-021-00437-z

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Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells

Abstract

Discussion

Cite This Study

Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells

Abstract

Discussion

Cite This Study

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