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Demonstrates good catalytic activity of Ir(I) complexes in hydrogenation and hydrosilylation, indicating effective synthesis methods.
The ambiphilic bicyclic (alkyl)(amino)carbenes ( Me/iPr BICAAC) upon reaction with [IrCl(COD)] 2 smoothly afford mononuclear Ir(I) complexes that have been spectroscopically and structurally characterized. These complexes exhibit good catalytic activity for transfer hydrogenation (TH) of 4-chlorobenzaldehyde using isopropyl alcohol (iPrOH), with turnover frequency values ranging between 6269 and 8093 h –1 . Choosing the covalent complex Ir( Me BICAAC)Cl(COD) as a catalyst, a wide array of carbonyls and imines functionalized with electron-withdrawing and electron-donating substituents have been surveyed and afforded their reduced products in moderate-to-good yields. No detachment of the BICAAC unit from the Ir center was observed upon prolonged heating of Ir( Me BICAAC)Cl(COD) in toluene- d 8 or isopropyl alcohol- d 8, which evidenced good thermal stability of the catalyst. Complex Ir( Me BICAAC)Cl(COD) was also found to be catalytically active for the hydrosilylation of a variety of aldehydes using triethylsilane (Et 3 SiH).
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Kaur et al. (2024) studied this question.
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