Why the study?
Do elevated symptoms of depression and distress early after lung transplantation predict increased long-term mortality?
Population
132 lung transplant recipients
Design
Cohort
Follow-up
up to 13.5 years (median 7.4 years)
Key result
Elevated symptoms of depression (HR 1.31, p=0.011) and general distress (HR 1.28, p=0.003) measured 6 months after lung transplantation were associated with increased long-term mortality.
Authors
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Negative affect post-lung transplant may predict mortality; leaves open need for prospective validation before screening changes.
Cohort (n=132)
Do elevated symptoms of depression and distress early after lung transplantation predict increased long-term mortality?
Hazard Ratio: 1.31
p-value: p=0.011
Elevated symptoms of depression and general distress measured 6 months after lung transplantation are independent predictors of long-term mortality.
Smith et al. (2015) conducted a cohort in Lung transplant recipients (n=132). Elevated symptoms of depression and distress vs. Lower levels of depression and distress was evaluated on Mortality (HR 1.31, p=0.011). Elevated symptoms of depression (HR 1.31, p=0.011) and general distress (HR 1.28, p=0.003) measured 6 months after lung transplantation were associated with increased long-term mortality.