Reference Ranges for Cerebral Oxygenation in Neonates During Immediate Transition After Birth: Differences Between Devices

Aim The aim was to define reference ranges for cerebral oxygen saturation (crSO 2 ‐ROOT) during immediate transition after birth in stable neonates. Methods In a prospective observational study, the crSO 2 ‐ROOT was continuously measured in neonates during the first 15 min after birth. The neonatal sensor was placed on the head and fixed with a bandage. Median values and 10th and 90th centiles were calculated for each minute. Additionally, cerebral fractional tissue oxygen extraction (cFTOE‐ROOT) was calculated using crSO 2 ‐ROOT and arterial oxygen saturation (SpO 2 ) measured with pulse oximetry. These crSO‐ROOT values were compared with already published reference ranges of cerebral oxygen saturation measured using different devices: crSO 2 ‐INVOS and cTOI‐NIRO. Results The data of 122 neonates (14 preterm/108 term neonates) were analysed. The crSO 2 ‐ROOT values had a similar course when compared to cTOI‐NIRO values, whereas crSO 2 ‐INVOS values were initially lower and exceeded during the first minutes after birth. Conclusion The present observational study added reference ranges of crSO 2 ‐ROOT in stable neonates immediately after birth. As there are differences regarding reference ranges of various near‐infrared spectroscopy (NIRS) devices, it is important to be aware of this information for future clinical use.