Key result
Lupus retinopathy is associated with active disease, lupus cerebritis, and worse overall survival.
Cohort (n=550)
In a prospective study of 550 patients with systemic lupus erythematosus (SLE), 41 were found to have retinopathy. Lupus retinopathy in the majority of cases consisted of a microangiopathy, with an excellent prognosis for vision. Five patients developed other complications that resulted in loss of visual acuity. Lupus retinopathy was associated with active SLE in 88% of patients and with lupus cerebritis in 73% of cases. Retinopathy in SLE was a marker of poor prognosis for survival.
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Stafford-Brady et al. (1988) conducted a cohort in Systemic lupus erythematosus (SLE) (n=550). Lupus retinopathy vs. No retinopathy was evaluated on Prevalence of retinopathy, complications, and association with other SLE manifestations and survival. Lupus retinopathy, present in 41 of 550 SLE patients, was associated with active SLE (88%) and lupus cerebritis (73%), and served as a marker of poor prognosis for survival.
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