MultiReGAME, a gamified multimodal station for rehabilitation: pilot study

Accessible rehabilitation technologies that combine motor and cognitive training can expand treatment options for people with neurological disorders. The aim of this study was to design and conduct a pilot evaluation of MultiReGAME, a compact, non-invasive, gamified multimodal rehabilitation system with multiple sensing modalities for training the upper and lower limbs, hands, wrists, and cognitive functions. The platform integrates adjustable force-threshold interaction, vertical displacement-based game control, joystick and button controls, tactile interaction, keyboard input, and visual and haptic feedback. Thirteen serious games with multiple difficulty levels and input options (including multiplayer modes) were developed to facilitate personalized training, and automatic post-session summaries were included for remote follow-up of session-level performance and adherence-related variables. A single-session pilot study was conducted with 25 participants, including healthy adults and adults with neurological conditions (Córdoba, Spain). Usability and user experience were assessed following standardized exposure to the platform. Both groups successfully completed the session, reporting high perceived usability and a generally positive user experience, particularly regarding stimulation, engagement, and novelty. No fatigue or device-related adverse events were observed. These findings support the preliminary feasibility of MultiReGAME for supervised rehabilitation with remote monitoring, although further studies are needed to assess long-term reliability, adherence, and clinical efficacy. Sensor-derived force and displacement signals were not used as clinical outcomes in this pilot study.