Using capnographic changes to assess pulmonary perfusion impairment during pulmonary surgery: animal experiments and clinical studies

Jinjun Shu; Huaiming Wang; Jiaxin Sun; Jiang Zou; Bin Hu; Hongwei Zhang; Xiaozun Yang; Xiang Wang; A Zhang; Yihao Zhu; Yumin Tang; Lei Ma

doi:10.1038/s41598-026-62273-0

July 16, 2026Scientific ReportsOpen Access

Using capnographic changes to assess pulmonary perfusion impairment during pulmonary surgery: animal experiments and clinical studies

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Key Points

The study aims to assess the potential of capnographic changes as indicators of pulmonary perfusion impairment during surgical procedures.
Conducted animal experiments and clinical studies to evaluate capnographic changes.
Utilized double-lumen tubes (DLT) to monitor pulmonary perfusion.
Registered under Chinese Clinical Trial Registry (ChiCTR2200065248; ChiCTR2500114855).
Identified that the 'chair-back' capnogram indicates real-time pulmonary perfusion impairment when DLT is employed.

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Implication

Evaluates capnographic indicators of pulmonary perfusion impairment during surgery, suggesting clinical relevance.

Abstract

gradient, the "chair-back" capnogram may serve as a potential real-time capnographic sign of pulmonary perfusion impairment when DLT is used.Trial registrationChinese Clinical Trial Registry http://www.chictr.org.cn (November 1, 2022; ChiCTR2200065248 and December 18, 2025; ChiCTR2500114855).

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Cite This Study

Shu et al. (2026) studied this question.

synapsesocial.com/papers/6a5c68af118b92953e3ed558 https://doi.org/10.1038/s41598-026-62273-0

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Using capnographic changes to assess pulmonary perfusion impairment during pulmonary surgery: animal experiments and clinical studies

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Using capnographic changes to assess pulmonary perfusion impairment during pulmonary surgery: animal experiments and clinical studies

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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