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July 19, 2026Nano LIFE

Advancements in Lipid Nanotechnology for the Treatment of Triple-Negative Breast Cancer: Mechanistic Insights and Future Prospects

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Authors

ICIssac V CherianIndo Soviet Friendship College of PharmacyHKHarpreet KaurKAKamre Aalam

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Overview

Review explores lipid nanotechnology improving drug delivery and treatment in triple-negative breast cancer, indicating promising future prospects.

Key Points

  • The aim is to address the challenges of treating triple-negative breast cancer (TNBC) using lipid nanotechnology.
  • Reviewed advancements in various lipid nanoparticle systems including liposomes and solid lipid nanoparticles.
  • Highlighted strategies for enhancing tumor targeting and reversing drug resistance.
  • Discussed pharmacokinetic, safety, and manufacturing challenges alongside pre-clinical evidence.
  • Lipid nanoparticles significantly improve targeting of chemotherapeutics to TNBC tumors.
  • Demonstrated potential for dual-targeting cancer stem cells and modulating the tumor microenvironment.
  • Indicated promising future directions for developing scalable lipid nanoparticle systems for TNBC treatment.

Cite This Study

Cherian et al. (2026) studied this question.

synapsesocial.com/papers/6a5c6939118b92953e3ed994https://doi.org/10.1142/s1793984426300165
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