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July 19, 2026Journal of OptometryOpen Access

Effect of active vision therapy on task-based saccadic and smooth pursuit performance in children with anisometropic amblyopia

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Authors

MKManisha KoiralaSBSanjeev BhattaraiJSJyoti Baba Shrestha

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Overview

Randomized trial evaluates the effects of active vision therapy on visual outcomes in children, suggesting improved efficacy.

Key Points

  • This study aims to evaluate the impact of Active Vision Therapy combined with occlusion on visual and motor skills in children with anisometropic amblyopia.
  • Forty children with anisometropic amblyopia were randomized into two groups: AVT–occlusion (n=23) and occlusion-only (n=17).
  • Measured outcomes included BCVA, stereopsis, contrast sensitivity, and task-based saccadic and smooth pursuit performance at multiple time points.
  • Therapies consisted of structured exercises and daily patching of the fellow eye.
  • Both groups showed improvement in BCVA and task-based performance at p < 0.05, with the AVT–occlusion group showing greater gains.
  • At three months, the AVT–occlusion group outperformed occlusion-only in BCVA (−0.13 logMAR, p = 0.01) and task-based performances (saccadic response time: −0.78 ms, p < 0.001).
  • Correlations were found between improved task performance and BCVA (saccadic ρ=-0.43, p = 0.006; smooth pursuit ρ=-0.53, p = 0.001).

Cite This Study

Koirala et al. (2026) studied this question.

synapsesocial.com/papers/6a5c6970118b92953e3edbd0https://doi.org/10.1016/j.optom.2026.100624
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effect of amblyopia on contrast sensitivity, color vision, and stereoacuity2017 · 4 citations
  2. 2Recasting the Smooth Pursuit Eye Movement System2004 · 506 citations
  3. 3Refractive adaptation in amblyopia: quantification of effect and implications for practice2004 · 204 citations
  4. 4A systematic review of Amblyopia prevalence among the children of the world2020 · 40 citations
  5. 5Effects of Anisometropic Amblyopia on Visuomotor Behavior, I: Saccadic Eye Movements2010 · 105 citations