Key result
Predictors of intracerebral haemorrhage in patients with previous cerebral ischaemia included age ≥60 years, systolic BP ≥140 mm Hg, and antihypertensive drugs.
Why the study?
What are the predictors of intracerebral haemorrhage in patients with a history of TIA or minor ischaemic stroke?
Cohort (n=12,648)
Yes
What are the predictors of intracerebral haemorrhage in patients with a history of TIA or minor ischaemic stroke?
Answers are grounded in this paper and cite their sources.
A risk model based on age, blood glucose, systolic blood pressure, and antihypertensive drug use can identify patients with prior TIA or minor stroke at high risk for intracerebral hemorrhage.
We developed a model identifying patients with previous cerebral ischaemia at increased risk of intracerebral haemorrhage (ICH). Based on data from eight cohorts, 107 ICHs were found to have occurred among 12 648 patients. Multivariate Cox regression analysis identified the following predictors: age (> or = 60 years, hazard ratio (HR) 2.07), blood glucose level (> or = 7 mmol/l, HR 0.33), systolic blood pressure (> or = 140 mm Hg, HR 2.17), and antihypertensive drugs (HR 1.53). The highest risk quartile was associated with five times more ICHs than the lowest quartile.
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M.J. Ariesen (2005) conducted a cohort in History of TIA or minor ischaemic stroke (n=12,648). Risk factors (age ≥60 years, blood glucose ≥7 mmol/l, systolic BP ≥140 mm Hg, antihypertensive drugs) vs. Absence of risk factors was evaluated on Intracerebral haemorrhage (ICH). Predictors of intracerebral haemorrhage in patients with previous cerebral ischaemia included age ≥60 years, systolic BP ≥140 mm Hg, and antihypertensive drugs.
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