Key result
Adolescent and adult females demonstrated a significantly higher HF/LF ratio compared to males, while ageing was associated with a significant decline in HRV power components.
Why the study?
Are there gender differences in age-associated changes in cardiac autonomic nervous activity as measured by HRV in healthy individuals aged 6 to 55 years?
Observational
Are there gender differences in age-associated changes in cardiac autonomic nervous activity as measured by HRV in healthy individuals aged 6 to 55 years?
Gender differences in age-related HRV changes are present in adolescents and adults, suggesting a potential role for female sex hormones in cardiac autonomic modulation.
Gender-specific HRV reference values may warrant consideration in autonomic assessments; leaves open whether differences alter cardiovascular risk prediction.
Ageing is associated with changes in cardiac autonomic control as measured by Heart Rate Variability (HRV). Not many studies have explored the influence of gender on age-related changes in cardiac autonomic regulation. This study evaluated the gender differences in age-associated changes in cardiac autonomic nervous activity by assessing HRV using frequency domain analysis of short-term stationary R-R intervals. HRV was studied in healthy males and females ranging in age from 6 to 55 years. Total power and absolute power in High-Frequency (HF) and Low-Frequency (LF) components as well as HF in normalized unit declined significantly with ageing. The HF/LF ratio was significantly higher in the adolescent and adult females compared to male of these age groups. This study suggests that gender differences exist in age-related changes in HRV. The finding that gender differences are limited to adolescent and adult age groups may indicate a role for female sex hormones in cardiac autonomic modulation.
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Moodithaya et al. (2011) conducted an observational in Healthy. Female gender and ageing vs. Male gender and younger age was evaluated on Heart Rate Variability (HRV) using frequency domain analysis. Adolescent and adult females demonstrated a significantly higher HF/LF ratio compared to males, while ageing was associated with a significant decline in HRV power components.
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