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A fully integrated and reconfigurable octa-channel bio-signal acquisition system-in-package (SiP), which enables the wireless measurement of electromyography (EMG), electrocardiogram (ECG), or electroencephalography (EEG), is presented in this article. Each chiplet contains an analog front end in combination with a channel-selection multiplexer, a successive-approximation-register analog–digital converter (SAR-ADC), an ultra-wideband transmitter (UWB-TX), a low-power on-chip crystal-based clock generation circuit, and a low-dropout voltage regulator, including voltage reference. The die occupies an area of 3. 64 mm 2 in a 180-nm 1P6M CMOS technology. A flexible acquisition of bio-potentials is possible due to the rail-to-rail (R–R) input dc tolerance and multiple bandwidth and gain modes (0. 2–128/512/2048 Hz, and 19. 9–53. 1 dB, respectively). In addition, a low total harmonic distortion (THD) of -51. 1 dB of the bio-signal acquisition analog front end (Bio-AFE) for bio-signal relevant levels and a high signal-to-noise-and-distortion ratio (SNDR) of 83. 0 dB of the SAR-ADC result in a high linearity of the recorded bio-signals. A low input-referred noise ranging from 2. 9 to 7. 1 Vrms, together with a high differential input impedance of 216 M and a common-mode rejection ratio (CMRR) of 81. 6 dB, is essential for the acquisition of the low-amplitude bio-signals. The low-power consumption of 0. 37–1 W per channel (mode-dependent) of the Bio-AFE and that of 1. 22 W per channel of the SAR-ADC, both from a 1-V supply, enable battery-or RF-powered applications in a small form factor.
Fath et al. (Mon,) studied this question.