Why the study?
Does dialysis improve survival, quality of life, and treatment burden compared to conservative care in patients aged ≥70 years with advanced CKD?
Population
366 patients aged ≥70 years with advanced chronic kidney disease in a non-academic teaching hospital in The…
Comparison
Dialysis pathway vs Conservative care
Design
Cohort
Key result
Conservative care in older patients with advanced chronic kidney disease significantly increased hospital-free days per year compared to dialysis (352.7 vs 282.7 days; IRR 1.15), while the survival benefit of dialysis was lost in patients aged ≥80 years or with severe comorbidity.
Authors
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Supports conservative care to reduce burden in older advanced CKD; leaves open randomized confirmation of survival and QoL effects.
Cohort (n=366)
No
Does dialysis improve survival, quality of life, and treatment burden compared to conservative care in patients aged ≥70 years with advanced CKD?
Relative Risk: 1.15 (95% CI 1.09–1.21)
Absolute Event Rate: 352.7% vs 282.7%
p-value: p=<0.001
Conservative care in older patients with advanced CKD provides similar quality of life and more hospital-free days at lower costs compared to dialysis, particularly in those ≥80 years or with severe comorbidity.
Verberne et al. (2018) conducted a cohort in Advanced chronic kidney disease (stage 4/5) (n=366). Conservative care vs. Dialysis was evaluated on Hospital free days per year (IRR 1.15, 95% CI 1.09-1.21, p=<0.001). Conservative care in older patients with advanced chronic kidney disease significantly increased hospital-free days per year compared to dialysis (352.7 vs 282.7 days; IRR 1.15), while the survival benefit of dialysis was lost in patients aged ≥80 years or with severe comorbidity.
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