Key result
Baseline apathy was significantly associated with the development of major depressive disorder after hip fracture (OR 1.09; 95% CI 1.03-1.16; P=.003), occurring in 46.2% vs 10.9% of patients.
Why the study?
What are the predictors of onset of major depressive disorder (MDD) in elderly persons after hip fracture?
Cohort (n=126)
No
What are the predictors of onset of major depressive disorder (MDD) in elderly persons after hip fracture?
Odds Ratio: 1.09 (95% CI 1.03–1.16)
Absolute Event Rate: 46.2% vs 10.9%
p-value: p=.003
Baseline apathy is a significant predictor of developing major depressive disorder in elderly patients following surgical fixation for hip fracture.
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May support apathy screening for MDD risk stratification after hip fracture in elderly patients; leaves open need for interventional trials.
Lenze et al. (2006) conducted a cohort in Hip fracture (n=126). Baseline apathy vs. Lower apathy scores was evaluated on Development of major depressive disorder (MDD) (OR 1.09, 95% CI 1.03-1.16, p=.003). Baseline apathy was significantly associated with the development of major depressive disorder after hip fracture (OR 1.09; 95% CI 1.03-1.16; P=.003), occurring in 46.2% vs 10.9% of patients.
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