Key result
A nurse-directed hypertension treatment algorithm reduced systolic blood pressure by 24.0 mm Hg compared to 17.0 mm Hg with standard physician care, but this 7.0 mm Hg difference was not statistically significant (p=0.14).
Why the study?
Does a nurse-directed treatment algorithm reduce systolic blood pressure in First Nations people with hypertension and type 2 diabetes?
Population
First Nations people with existing hypertension and type 2 diabetes
Comparison
Home care nurse following a predefined treatment… vs Treatment decisions made by each subject's…
Design
RCT, randomized
Follow-up
12 months
Authors
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Nurse-led community hypertension care may improve BP control in First Nations diabetes patients; leaves open need for confirmatory trials.
RCT (n=99)
Open-label
Permuted block design, stratified by 7 reserves
Yes
Does a nurse-directed treatment algorithm reduce systolic blood pressure in First Nations people with hypertension and type 2 diabetes?
Mean Difference: -7
Absolute Event Rate: -24% vs -17%
p-value: p=0.14
A nurse-directed hypertension treatment strategy was more effective in lowering diastolic, but not systolic, blood pressure compared to standard physician-directed care in First Nations people with diabetes.
Sheldon W. Tobe (2006) conducted an RCT in Type 2 diabetes mellitus and persistent hypertension (n=99). Nurse-directed hypertension treatment algorithm vs. Primary care physician treatment decisions was evaluated on Mean change in systolic blood pressure from baseline to 12 months (MD -7.0, p=0.14). A nurse-directed hypertension treatment algorithm reduced systolic blood pressure by 24.0 mm Hg compared to 17.0 mm Hg with standard physician care, but this 7.0 mm Hg difference was not statistically significant (p=0.14).
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