Key result
The global burden of pulmonary arterial hypertension is likely underestimated, with prevalence estimated at 2-16 cases per million children and up to 4-6% in at-risk groups with schistosomiasis.
Paediatric pulmonary arterial hypertension has distinct epidemiological characteristics and requires specific management strategies different from adult PAH.
Paediatric pulmonary arterial hypertension should be treated specifically and differently from adult pulmonary arterial hypertension http://ow.ly/mzPDT Pulmonary arterial hypertension (PAH) is a progressive, angio-obliterative disease leading to increased pulmonary vascular resistance, right heart failure, and death in ,25-60% of PAH patients 5 years after diagnosis The estimated prevalence of PAH is 15-50 cases per million adults [4-6] and 2-16 cases per million children In certain at-risk groups, however, the occurrence of PAH is substantially higher. For example, the prevalence is 0.5% in HIV-infected patients [10] and 4-6% in schistosomiasis These diseases are far more common in developing countries with limited health care and, thus, the real burden of PAH worldwide is probably underestimated.
No takes yet. Share an insight, caveat, or question.
Hansmann et al. (2013) conducted a review in Paediatric pulmonary arterial hypertension. The global burden of pulmonary arterial hypertension is likely underestimated, with prevalence estimated at 2-16 cases per million children and up to 4-6% in at-risk groups with schistosomiasis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: