Key result
Advances in multimodality imaging, particularly cardiac magnetic resonance, enable imaging-guided therapy to detect inflammation and potentially prevent or reverse constrictive pericarditis.
Why the study?
Constrictive pericarditis can cause heart failure and poor quality of life, making early recognition critical as multimodality cardiac imaging evolves to facilitate earlier diagnosis and management.
Multimodality imaging, especially cardiac magnetic resonance, is essential for the precision diagnosis of constrictive pericarditis and enables imaging-guided therapy to manage pericardial inflammation.
May prompt CMR for pericardial inflammation; leaves open prospective validation of guided therapy outcomes.
INTRODUCTION: Constrictive pericarditis (CP) can result from uncontrolled inflammation of the pericardium. This can be due to various etiologies. CP can lead to both left- and right-sided heart failure with associated poor quality of life, so early recognition is key. The evolving role of multimodality cardiac imaging allows for earlier diagnosis and facilitates management to help mitigate this adverse outcome. AREAS COVERED: This review discusses the pathophysiology of constrictive pericarditis, chronic inflammation and autoimmune etiologies, clinical presentation of CP, and advances in multimodality cardiac imaging for diagnosis and management. Echocardiography and cardiac magnetic resonance (CMR) imaging remain cornerstone modalities to evaluate this condition, whereas additional imaging modalities such as computed tomography and FDG-positron emission tomography can provide complementary information. EXPERT OPINION: Advances in multimodality imaging allow for a more precision diagnosis of constrictive pericarditis. There has been a paradigm shift in pericardial disease management with advances in multimodality imaging, especially CMR, to detect subacute and chronic inflammation. This has enabled imaging-guided therapy (IGT) to both help prevent and potentially reverse established constrictive pericarditis.
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Kafil et al. (2023) conducted a review in Constrictive pericarditis and pericardial inflammation. Multi-modality imaging was evaluated. Advances in multimodality imaging, particularly cardiac magnetic resonance, enable imaging-guided therapy to detect inflammation and potentially prevent or reverse constrictive pericarditis.
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