⌘+K

Pulse Explore Communities Researchers Journals

Browser extensionInstagram

Home Communities Explore

November 12, 2015OncoImmunologyOpen Access

CD137 and CD137L signals are main drivers of type 1, cell-mediated immune responses

Bhushan Dharmadhikari Meihui Wu Nur Sharalyn Abdullah Sakthi Rajendran Nur Diana Binte Ishak Emily Nickles Zulkarnain Harfuddin Herbert Schwarz

View Full Paper

Ask AI

Bookmark

Share

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Abstract

T cells and NK cells inhibit other T cell subsets, thereby promoting antitumor responses and mitigating non-type 1 auto-immune diseases.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Dharmadhikari et al. (2015) studied this question.

synapsesocial.com/papers/6a5d9d6f5a427dda4a033eb6 https://doi.org/10.1080/2162402x.2015.1113367

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 10 related papers. Consider them for comparative context:

14-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapyReview · 2014 · 156 citations
2SA-4-1BBL and Monophosphoryl Lipid A Constitute an Efficacious Combination Adjuvant for Cancer VaccinesOriginal Research · 2014 · 42 citations
3Targeting 4-1BB Costimulation to the Tumor Stroma with Bispecific Aptamer Conjugates Enhances the Therapeutic Index of Tumor ImmunotherapyOriginal Research · 2014 · 96 citations
44-1BBL Cooperates with B7-1 and B7-2 in Converting a B Cell Lymphoma Cell Line into a Long-Lasting Antitumor VaccineOriginal Research · 1999 · 125 citations
5Tumor Expression of 4-1BB Ligand Sustains Tumor Lytic T CellsOriginal Research · 2003 · 37 citations
6Combined vaccination and immunostimulatory antibodies provides durable cure of murine melanoma and induces transcriptional changes associated with positive outcome in human melanoma patientsOriginal Research · 2012 · 28 citations
7CD137 stimulation enhances the vaccinal effect of anti-tumor antibodiesOriginal Research · 2014 · 15 citations
8cDNA sequences of two inducible T-cell genes.Original Research · 1989 · 401 citations
9Alteration of macrophage infiltrates in the tumor immune microenvironment following Janus kinase 1 (JAK) inhibition: analysis from a prospective clinical trial in LeiomyosarcomaOncoImmunology · 2026
10RIG-I is essential for radiation-induced IFN-β production and PD-L1/PD-L2 upregulation in HPV-negative head and neck squamous cell carcinoma cellsOncoImmunology · 2026

More from OncoImmunology

More from National University of Singapore