Key result
FAP targeting shows promise for cancer diagnosis and treatment but requires further clinical evaluation.
Why the study?
The multifaceted roles, molecular functionalities, regulatory mechanisms, prognostic significance, and clinical utility of fibroblast activation protein in cancer diagnosis and treatment needed comprehensive review.
FAP is a promising target for accurate tumor diagnosis and multiple therapeutic strategies in cancer.
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FAP review supports expanded diagnostic/therapeutic research; leaves open clinical adoption pending prospective validation.
Zhang et al. (2023) conducted a review in Cancer. FAP targeting strategies (e.g., FAPI, CAR T cell therapy) was evaluated. Fibroblast Activation Protein (FAP) serves as a promising target for cancer diagnosis and treatment, though multiple therapeutic strategies require further clinical evaluation.
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