Outcomes of patients with HIV and COVID-19 co-infection: a systematic review and meta-analysis
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Discussion
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Implication
Systematic review summarizes hospitalization and mortality risks for HIV co-infected COVID-19 patients, suggesting increased risk.
Key Points
- This research aims to evaluate the impact of HIV on adverse outcomes in COVID-19 patients.
- Systematic review of literature from PubMed, EMBASE, Web of Science, and SCOPUS up to October 25, 2021.
- Inclusion of 44 studies representing 38,971,065 COVID-19 patients, using a random-effects model to pool data.
- Assessment of hospitalization and mortality risks associated with HIV in COVID-19 patients through unadjusted and adjusted analyses.
- Pooled prevalence of HIV among COVID-19 patients was 26.9 ‰ (95% CI 22.7-31.3).
- HIV-positive individuals had a higher likelihood of hospitalization (OR: 1.49; 95% CI 1.01-2.21).
- Adjusted analysis revealed HIV was associated with increased mortality risk (hazard ratio: 1.76; 95% CI 1.31-2.35).
Cite This Study
Danwang et al. (2022) studied this question.