Key result
Pulmonary vascular disease markedly reduced survival in patients with secundum atrial septal defects, with 25% alive in 1966 compared to 91.3% of those with normal pulmonary vascular resistance.
Why the study?
How does the presence of pulmonary vascular disease affect survival in patients with secundum atrial septal defects?
Cohort (n=48)
How does the presence of pulmonary vascular disease affect survival in patients with secundum atrial septal defects?
Absolute Event Rate: 25% vs 91.3%
The presence of pulmonary vascular disease markedly reduces survival in patients with secundum atrial septal defects, supporting the recommendation for early surgical correction before its development.
No takes yet. Share an insight, caveat, or question.
Pulmonary vascular disease markedly worsens survival in secundum ASD; leaves open whether early closure alters outcomes in modern cohorts.
James E. Dalen (1967) conducted a cohort in Secundum atrial septal defects (n=48). Pulmonary vascular disease vs. Normal pulmonary vascular resistance was evaluated on Survival to 1966. Pulmonary vascular disease markedly reduced survival in patients with secundum atrial septal defects, with 25% alive in 1966 compared to 91.3% of those with normal pulmonary vascular resistance.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: