Key result
Volumetric and end-tidal capnography reflected reductions in cardiac output with modest correlations (ρ=0.53 and ρ=0.47), but only end-tidal capnography detected CO reduction by ROC analysis.
Why the study?
Detecting cardiac output changes can help identify hypovolemia or cardiac dysfunction, leading authors to evaluate whether EtCO2 and VtCO2 reflect sudden changes in cardiac output.
Do changes in end-tidal CO2 (EtCO2) and eliminated volume per breath (VtCO2) reflect sudden changes in cardiac output in mechanically ventilated patients early after open heart surgery?
Population
33 ventilated patients after open heart surgery
Comparison
Right ventricular pacing vs passive leg raise
Design
Physiological interventional study
Authors
Loading...
EtCO2/VtCO2 may track acute CO changes in instability; leaves open validation before clinical use.
Do changes in end-tidal CO2 (EtCO2) and eliminated volume per breath (VtCO2) reflect sudden changes in cardiac output in mechanically ventilated patients early after open heart surgery?
In mechanically ventilated patients after open heart surgery, EtCO2 and VtCO2 modestly reflect reductions in cardiac output, with EtCO2 showing fair predictive ability for detecting >15% CO reductions.
Hoff et al. (2019) studied Mechanically ventilated patients early after open heart surgery (n=33). Volumetric and end-tidal capnography was evaluated on Detection of cardiac output changes. Volumetric and end-tidal capnography reflected reductions in cardiac output with modest correlations (ρ=0.53 and ρ=0.47), but only end-tidal capnography detected CO reduction by ROC analysis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: