Key result
Pulmonary vein thromboses were identified in 61% (35 of 57) of elderly patients with chest pain, suggesting they may be a common cause of microvessel occlusion and cardiovascular disease.
Why the study?
Do pulmonary vein thromboses cause and promote cardiovascular disease via genetic modulation in elderly patients with chest pain?
Do pulmonary vein thromboses cause and promote cardiovascular disease via genetic modulation in elderly patients with chest pain?
Pulmonary vein thromboses may be common in elderly patients with chest pain and could potentially promote cardiovascular disease through microvascular occlusion and genetic modulation.
May warrant further study in elderly chest pain but should not change practice; leaves open causal role in microvessel occlusion.
Pulmonary vein thromboses (PVTs) are believed to be rare; however, using 64-slice multidetector CT (64-MDCT), I have reported a number of cases of PVT in elderly patients with chest pains since 2012 [1-10].In 2014, I reported that 61% (35 patients) of 57 elderly patients with chest pain had PVTs [5], which suggests that PVTs are common in elderly patients with chest pain.PVTs can release microclots that can occlude the microarteries of all organs, which inhibits the supply of oxygen and nutrients by inhibiting the arterial flow.Such conditions can cause and promote heart failure and activate nuclear respiratory factor-1 (NRF-1; CGCRTGCGCR), metal responsive transcription factor-
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Hidekazu Takeuchi (2015) conducted a review in Chest pain (n=57). Pulmonary vein thromboses was evaluated on Presence of pulmonary vein thromboses. Pulmonary vein thromboses were identified in 61% (35 of 57) of elderly patients with chest pain, suggesting they may be a common cause of microvessel occlusion and cardiovascular disease.
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